Comparison of Existing Clinical Scoring Systems in Predicting Severity and Prognoses of Hyperlipidemic Acute Pancreatitis in Chinese Patients

نویسندگان

  • Lei Qiu
  • Rui Qing Sun
  • Rong Rong Jia
  • Xiu Ying Ma
  • Li Cheng
  • Mao Chun Tang
  • Yan Zhao
  • Somchai Amornyotin.
چکیده

It is important to identify the severity of acute pancreatitis (AP) in the early course of the disease. Clinical scoring systems may be helpful to predict the prognosis of patients with early AP; however, few analysts have forecast the accuracy of scoring systems for the prognosis in hyperlipidemic acute pancreatitis (HLAP). The purpose of this study was to summarize the clinical characteristics of HLAP and compare the accuracy of conventional scoring systems in predicting the prognosis of HLAP. This study retrospectively analyzed all consecutively diagnosed AP patients between September 2008 and March 2014. We compared the clinical characteristics between HLAP and nonhyperlipidemic acute pancreatitis. The bedside index for severity of acute pancreatitis (BISAP), Ranson, computed tomography severity index (CTSI), and systemic inflammatory response syndrome (SIRS) scores were applied within 48 hours following admission. Of 909 AP patients, 129 (14.2%) had HLAP, 20 were classified as severe acute pancreatitis (SAP), 8 had pseudocysts, 9 had pancreatic necrosis, 30 had pleural effusions, 33 had SIRS, 14 had persistent organ failure, and there was 1 death. Among the HLAP patients, the area under curves for BISAP, Ranson, SIRS, and CTSI in predicting SAP were 0.905, 0.938, 0.812, and 0.834, 0.874, 0.726, 0.668, and 0.848 for local complications, and 0.904, 0.917, 0.758, and 0.849 for organ failure, respectively. HLAP patients were characterized by younger age at onset, higher recurrence rate, and being more prone to pancreatic necrosis, organ failure, and SAP. BISAP, Ranson, SIRS, and CTSI all have accuracy in predicting the prognosis of HLAP patients, but each has different strengths and weaknesses.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Comparison of BISAP, Ranson, MCTSI, and APACHE II in Predicting Severity and Prognoses of Hyperlipidemic Acute Pancreatitis in Chinese Patients

In recent years, with the developing of living standard, hyperlipidemia becomes the second major reason of acute pancreatitis. It is important to predict the severity and prognosis at early stage of hyperlipidemic acute pancreatitis (HLAP). We compared the BISAP, Ranson, MCTSI, and APACHE II scoring system in predicting MSAP and SAP, local complications, and mortality of HLAP. A total of 326 di...

متن کامل

Artificial neural networks: applications in predicting pancreatitis survival

Artificial neural networks are intelligent systems that have successfully been used for prediction in different medical fields. In this study, the efficiency of a neural network for predicting the survival of patients with acute pancreatitis is compared with days-of-survival obtained from patients. A three- layer back-propagation neural network was developed for this purpose. Clinical data (e.g...

متن کامل

Artificial neural networks: applications in predicting pancreatitis survival

Artificial neural networks are intelligent systems that have successfully been used for prediction in different medical fields. In this study, the efficiency of a neural network for predicting the survival of patients with acute pancreatitis is compared with days-of-survival obtained from patients. A three- layer back-propagation neural network was developed for this purpose. Clinical data (e.g...

متن کامل

The comparison of apache ii scores with neutrophil lymphocyte ratio and red cell distribution width for the prediction of prognosis of patients with acute pancreatitis

Acute pancreatitis Acute pancreatitis (AP) is an inflammatory process of pancreatic tissue, which can affect other distant organ systems. Its severity can range from mild inflammation to severe, progressive pancreatic necrosis, and it can lead to multiorgan failure that may have a mortality rate as high as 20% to 30% [1]. Several scoring systems have been proposed to determine its severity. Amo...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 94  شماره 

صفحات  -

تاریخ انتشار 2015